经阴道超声联合血清β-hCG及子宫动脉血流参数对不全流产保守治疗与手术干预的预判价值
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镇平县中医院

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Predictive value of transvaginal ultrasound combined with serum β-hCG and uterine artery blood flow parameters for conservative treatment and surgical intervention of incomplete abortion
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Zhenping County Hospital of Traditional Chinese Medicine

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    摘要:

    目的 探讨经阴道超声(transvaginal ultrasound,TVUS)联合血清β-人绒毛膜促性腺激素(β-human chorionic gonadotropin,β-hCG)及子宫动脉血流参数在不全流产保守治疗与手术干预决策中的预判价值。方法 回顾性选取2023年2月至2026年2月于镇平县中医院就诊的92例不全流产患者,按最终临床处置分为保守治疗成功组(n=51)与手术干预组(n=41)。比较两组间各指标差异,采用受试者操作特征(receiver operator characteristic,ROC)曲线分析单项及联合指标对手术干预需求的预测效能。结果 手术干预组残留组织最大径、Adler分级Ⅲ级占比、血清β-hCG水平及子宫动脉PI、RI均显著高于保守治疗成功组(均P<0.05);ROC曲线显示,TVUS残留径线、β-hCG、子宫动脉RI三项联合预测的曲线下面积(area under the curve,AUC)为0.912(95%CI:0.861~0.963),最佳截断值为预测概率>0.52,敏感度和特异度分别为86.7%和89.4%,优于任一单项指标。结论 TVUS联合血清β-hCG及子宫动脉血流参数可有效区分不全流产需手术干预的高危病例,为临床个体化决策提供客观依据。

    Abstract:

    Objective To investigate the predictive value of transvaginal ultrasound (TVUS) combined with serum β-human chorionic gonadotropin (β-hCG) and uterine artery blood flow parameters in the conservative treatment and surgical intervention decisionmaking of incomplete abortion. Methods A total of 92 patients with incomplete abortion who attended Zhenping Chinese Medicine Hospital from February 2023 to February 2026 were retrospectively selected. According to the final clinical treatment, they were divided into conservative treatment successful group (n=51) and surgical intervention group (n=41). The differences of each index between the two groups were compared, and the predictive efficacy of single and combined indexes on surgical intervention demand was analyzed by receiver operator characteristic (ROC) curve. Results The maximum diameter of residual tissue, proportion of Adler grade Ⅲ, serum β -hCG level and PI, RI of uterine artery in the surgical intervention group were significantly higher than those in the conservative successful group (all P<0.05). The ROC curve showed that the combined prediction of TVUS residual diameter, β-hCG and uterine artery RI was 0.912 (95%CI: 0.861?0.963), the optimal cutoff value was when the prediction probability was greater than 0.52, and the sensitivity and specificity were 86.7% and 89.4%, respectively, which were better than any single index. Conclusion TVUS combined with serum β-hCG and uterine artery blood flow parameters can effectively distinguish high-risk cases of incomplete abortion requiring surgical intervention, and provide objective basis for clinical individualized decision-making.

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李庆霞.经阴道超声联合血清β-hCG及子宫动脉血流参数对不全流产保守治疗与手术干预的预判价值[J].生物医学工程学进展,2026,(4):80-83

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  • 收稿日期:2026-09-04
  • 最后修改日期:2026-09-18
  • 录用日期:2026-09-21
  • 在线发布日期: 2026-10-20
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