With the advancement of modern hospital infrastructure, there has been a significant increase in both the quantity and technical sophistication of medical equipment. Consequently, the demand for applied biomedical engineering (BME) talent is on the rise. Practical teaching plays a crucial role in cultivating such specialized engineering talent. As a result, numerous Chinese universities have begun to emphasize the establishment of off-campus practice bases. Currently, many medical institutions undertake internship teaching responsibilities for BME students from universities. However, hospitals still lack a structured internship teaching system specifically designed for BME majors, necessitating the exploration of a scientific and systematic internship training model. In response to this need, this paper proposes a progressive teaching framework based on the cultivation of engineering practical skills, drawing inspiration from Miller’s Pyramid Model. This scientifically practice-oriented teaching method has substantially enhanced the quality of intern’s practical training in the medical engineering department of the hospital. It is anticipated that this method will cultivate more high-caliber BME professionals with robust practical abilities for society.