Objective To explore the application effect of intelligent pharmaceutical management information platform in hospital pharmaceutical management. Methods A retrospective study was conducted to collect information from 30 staff members of the Pharmacy Department of the 989th Hospital of the Joint Logistics Support Force. The study period was from January 2023 to December 2023, and the patients were grouped according to the implementation of hospital pharmaceutical management. The implementation of traditional pharmaceutical management from January 2023 to June 2023 was included in the control group, and the implementation of intelligent pharmaceutical management information platform management from July 2023 to December 2023 was included in the observation group. The quality of pharmaceutical management and the satisfaction of staff and patients with the implementation of management were evaluated using a self-made hospital satisfaction survey, and the incidence of adverse events in both groups was recorded. Results The observation group had higher scores in drug procurement and storage, drug preparation and use, drug quality management and supervision, patient drug retrieval process, and total score than the control group (P<0.05). The incidence of adverse events in the observation group was lower than that in the control group (P <0.05). The satisfaction scores of the observation group staff and patients were higher than those of the control group (P<0.05). Conclusions Compared with traditional pharmaceutical management, the application of intelligent pharmaceutical management information platform for pharmaceutical management has higher management quality, which helps to reduce the incidence of adverse events during management and improve the satisfaction of staff and patients.