CT 增强三期扫描与增强 MRI 在小肝癌及术后复发微小病灶诊断中的比较研究
CSTR:
作者:
作者单位:

永煤集团总医院

作者简介:

通讯作者:

中图分类号:

基金项目:


A Comparative Study of Enhanced Triple-Phase CT and Enhanced MRI in the Diagnosis of SHCC and Postoperative Recurrent Small Lesions
Author:
Affiliation:

Yongmei Group General Hospital

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的 对比计算机断层扫描( Computed Tomography, CT)增强三期扫描与增强磁共振成像( Magnetic Resonance Imaging, MRI)在小肝癌( Small Hepatocellular Carcinoma, SHCC)及术后复发微小病灶中的诊断价值。 方法 选取 2021 年 7 月至 2024 年 6 月在永煤集团总医院影像中心就诊的疑似 SHCC 患者 166 例,根据检查方式不同,将行 CT 增强三期扫描检查的 83 例患者作为增强 CT 组,行增强 MRI 检查的 83 例患者作为增强 MRI 组,以术后病理结果为金标准,对比两组的一致性、诊断效能及影像学表现。以术后复发微小病灶的病理检查为金标准,分析两组检查与病理检查的一致性和诊断效能。 结果 增强 CT 组共检出阳性 19 例、阴性 64 例,术后病理证实 SHCC 阳性 26 例、阴性 57 例;增强 MRI 组共检出阳性 37 例、阴性 46 例,术后病理证实 SHCC 阳性 34 例、阴性 49 例。增强 MRI 组诊断 SHCC 的灵敏度为 97.06%、准确率为93.98%、阴性预测值为 97.83%,高于增强 CT 组的灵敏度 57.69%、准确率 81.93%、阴性预测值 82.81%,差异有统计学意义( χ2=14.270, 5.685, 6.207, P<0.05);增强 MRI 组诊断与病理检查一致性( Kappa 值 =0.877, P<0.001)高于增强 CT 组( Kappa值 =0.547, P<0.001)。两组特异度、阳性预测值比较,差异均无统计学意义( P>0.05)。增强 CT 组与增强 MRI 组动脉期信号对比差异有统计学意义( χ2=6.470, P<0.05);门脉期、延迟期信号对比无明显差异( P>0.05)。 5 个月后复查,对检出疑似微小病灶的 56 例患者进行诊断分析,增强 CT 组发现复发微小病灶阳性 22 例、阴性 34 例,术后病理证实复发微小病灶阳性 27 例、阴性 29 例;增强 MRI 组发现复发微小病灶阳性 32 例、阴性 24 例,术后病理证实复发微小病灶阳性 29 例、阴性 27 例。增强 MRI 组诊断复发微小病灶的灵敏度为 96.55%、准确率为 91.07%、阴性预测值为 95.83%,高于增强 CT组的灵敏度 66.67%、准确率 76.79%、阴性预测值 73.53%,差异有统计学意义( χ2=8.513, 4.236, 4.905, P<0.05);增强MRI 组诊断复发微小病灶与病理检查一致性( Kappa 值 =0.821, P<0.001)高于增强 CT 组( Kappa 值 =0.532, P<0.001)。两组特异度、阳性预测值比较,差异均无统计学意义( P>0.05)。 结论 增强 MRI 诊断 SHCC 与 CT 增强三期扫描对比,具有更高的诊断价值,对复发微小病灶的检出灵敏度和准确率均较高。

    Abstract:

    Objective To compare the diagnostic value of enhanced triple-phase computer tomography (CT) with enhanced magnetic resonance imaging (MRI) in small hepatocellular carcinoma (SHCC), and postoperative recurrent small lesions. Methods A total of 166 patients with suspected SHCC from Yongmei Group General Hospital between July 2021 and June 2024 were selected and divided into two groups: 83 undergoing enhanced triple-phase CT scanning were assigned to enhanced CT group, and 83 undergoing enhanced MRI were assigned to enhanced MRI group. Postoperative pathological results were used as the gold standard to compare the consistency, diagnostic efficacy, and imaging findings between the two groups. For postoperative recurrent small lesions, pathological examination was also used as the reference to compare the consistency and diagnostic efficacy of the two groups. Results In the enhanced CT group, 19 cases were positive and 64 cases were negative by detection, while postoperative pathology confirmed 26 cases of SHCC positive and 57 cases negative. In the enhanced MRI group, 37 cases were positive and 46 cases were negative by detection, while postoperative pathology confirmed 34 cases of SHCC positive and 49 cases negative. The sensitivity of the enhanced MRI group for diagnosing SHCC was 97.06%, with an accuracy of 93.98%,and the negative predictive value was 97.83%, which were higher than the sensitivity of 57.69%, accuracy of 81.93%, and negative predictive value of 82.81% in the enhanced CT group. The differences were statistically significant (χ2=14.270,5.685, 6.207, P<0.05). The consistency of diagnosis and pathological examination (Kappa value=0.877, P<0.001) in the enhanced MRI group was higher than that in the enhanced CT group (Kappa value=0.547, P<0.001). There were no statistically significant differences in specificity and positive predictive value between the two groups (P >0.05). The difference in arterial phase signals between the enhanced CT group and the enhanced MRI group was statistically significant (χ2=6.470, P<0.05), while no significant differences were observed in the portal vein phase and delayed phase signals (P>0.05). At the 5-month follow-up, diagnostic analysis was performed on 56 patients with detected suspected small lesions. In the enhanced CT group, 22 cases were positive for recurrent small lesions and 34 cases were negative, while postoperative pathology confirmed 27 cases of recurrent small lesions positive and 29 cases negative. In the enhanced MRI group, 32 cases were positive for recurrent small lesions and 24 cases were negative, while postoperative pathology confirmed 29 cases of recurrent small lesions positive and 27 cases negative. The sensitivity of the enhanced MRI group for diagnosing recurrent small lesions was 96.55%, with an accuracy of 91.07%, and the negative predictive value was 95.83%, which were higher than the sensitivity of 66.67%, accuracy of 76.79%, and negative predictive value of 73.53% in the enhanced CT group. The differences were statistically significant (χ2=8.513, 4.236, 4.905, P<0.05). The consistency of diagnosis of recurrent small lesions and pathological examination (Kappa value=0.821, P<0.001) in the enhanced MRI group was higher than that of the enhanced CT group (Kappa value=0.532, P<0.001). There were no statistically significant differences in specificity and positive predictive value between the two groups (P>0.05). Conclusion Enhanced MRI has higher diagnostic value than enhanced triple-phase CT for SHCC and superior sensitivity and accuracy in diagnosing recurrent small lesions.

    参考文献
    相似文献
    引证文献
引用本文

刘铜锁. CT 增强三期扫描与增强 MRI 在小肝癌及术后复发微小病灶诊断中的比较研究[J].生物医学工程学进展,2025,(5):607-613

复制
分享
相关视频

文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2025-01-08
  • 最后修改日期:2025-01-14
  • 录用日期:2025-01-14
  • 在线发布日期: 2025-11-24
  • 出版日期:
文章二维码