The background of the construction of “New Engineering” has put forward new requirements for the construction of engineering courses, and highlighted the urgency and necessity of ideological and political construction in engineering courses. Based on the goals of talent cultivation in the construction of new engineering disciplines and the characteristics of biomedical engineering courses, a “3+5+N” model of ideological and political education in biomedical engineering courses under the background of new engineering disciplines has been constructed. Adhere to the principle of integrating theory with practice, value with knowledge, and problem orientation with goal orientation, we have established the concept of integrating emerging technologies, development patterns, multiple resources, various forces, and mission responsibilities, as well as organically combind N teaching methods. As a professional technical course in the field of biomedical engineering, “Active Medical Equipment and Detection Evaluation” uses the “3+5+N” model to carry out teaching practice. The course achieves the unity of value shaping, knowledge imparting, and ability cultivation, and provides reference for the ideological and political education of biomedical engineering courses in the context of new engineering disciplines.