In order to implement the educational concept of “building morality and cultivating people” in universities, curriculum-based ideological and political education has become an important innovation field of ideological and political education in colleges and universities. In order to solve the difficulties and poor effect of ideological and political integration in the engineering courses, the “Medical Device System Design” teaching team conducted in-depth exploration and applied the integration of ideological and political elements. Based on the characteristics of science and engineering college students, the teaching team found ideological and political elements, and infiltrated the whole process of ideological and political education into the teaching process. To achieve the goal of educating people in the whole process and moistening everything silently, the teaching team adopt online and offline blended teaching method of guidance before class，implementation in class, reinforcement after class. Combined with self-made micro-course and virtual simulation platform, it provides a new method and perspective for ideological and political education in engineering courses.