Physiology, body temperature is divided into skin temperature and core body temperature. The stability of the core body temperature is one of the necessary conditions for the normal operations of cells, organs and many physiological reactions in the human body. This article introduces the application of zero heat flux method, single heat flux method, dual heat flux method, and dual sensor measurement model in core body temperature measurement in heat flux method. The differences among the methods were compared from the aspects of principle, sensor structure, advantages and disadvantages. The size, material, sensor model and measurement accuracy of different models based on heat flux method were summarized. At the same time, the measurement methods of core body temperature are summarized and prospected.